Searchable abstracts of presentations at key conferences in endocrinology

ea0016p201 | Diabetes and cardiovascular diseases | ECE2008

No genetic impact of the SOCS3-gene on T2DM

Fischer Antje , Fisher Eva , Moehlig Matthias , Osterhoff Martin , Weickert Martin O , Pfeifer Andreas FH , Boeing Heiner , Spranger Joachim

The diabetic epidemic is increasing worldwide. The suppressor of cytokine signaling 3 (SOCS3) provides a link between cytokine action and their negative consequences on insulin signaling. This potential influence on the development of T2DM makes the gene a potential candidate gene for type 2 diabetes.We investigated the one haplotype tagging single nucleotide polymorphism (htSNP) rs4969168 to examine the impact on T2DM in two independent study population...